Development of a hydroxyapatite nanoparticle-based gel for enamel remineralization —A physicochemical properties and cell viability assay analysis
Chotimah, Yusuf Y., Amalina R., Sari M., Ramadhanti D.M., Ana I.D.
Abstract
Nano-hydroxyapatite (nHA) was synthesized from abalone mussel shells (Haliotis asinina) using a precipitation method, and gel HA-Abalone was developed using the carbomer materials with concentrations of 0, 10, 20, 30, and 40 wt%. The specimens used were 25 freshly extracted caries-free premolar teeth, and the treatment was done twice a day for 14 days. Gel HA-Abalone 20 wt%, with a crystallite size of 14.70±1.21 nm, was the best concentration to achieve the best remineralization (~863 VHN) of the superficial layer. Based on the results of cell viability assay on gel HA-Abalone 20 wt%, the growth of NIH/3T3 cells was inhibited beginning at a gel concentration of 1,000 µg/mL, and the half maximal inhibitory concentration (IC<inf>50</inf>) value was 1,497 µg/mL. Based on to the one-way analysis of variance (ANOVA), the result reflected statistically significant differences in the average of the cell viability and enamel surface microhardness values (p<0.05).
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Camboni T., Cotti E., Dettori C., Simbula G.
Cytotoxic effects of zoom® whitening product in human fibroblasts
Abrantes A.M., Abrantes A.M., Abrantes A.M., Abrantes A.M., Botelho M.F., Botelho M.F., Botelho M.F., Botelho M.F., Cabrita A., Cabrita A., Carrilho E., Carrilho E., Carrilho E., Carrilho E., Casalta-Lopes J., Casalta-Lopes J., Coelho A.S., Coelho A.S., Coelho A.S., Coelho A.S., Ferreira M.M., Ferreira M.M., Ferreira M.M., Ferreira M.M., Goncalves A.C., Goncalves A.C., Goncalves A.C., Goncalves A.C., Laranjo M., Laranjo M., Laranjo M., Laranjo M., Marto C.M., Marto C.M., Marto C.M., Marto C.M., Paula A., Paula A., Paula A., Paula A., Sarmento-Ribeiro A.B., Sarmento-Ribeiro A.B., Sarmento-Ribeiro A.B., Sarmento-Ribeiro A.B.
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Kulkarni V.K., Sharma D.S., Vyavhare S.
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Abdolazimi Z., Ekrami M, Malekafzali B, Mirfasihi A
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Evdokimova A.Y., Kunin A.A., Moiseeva N.S.
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Cai Q., Chen N., Chen Z., Cong C., Deng X., Guan B., Kishen A., Li T., Li Y., Lu D., Que K., Wang H., Xiao Z., Yang J., Yang X., Zhang Q., Zhang X.
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Carolan P., Deb S., Lemoine P., Lubarsky G.V., Meenan B.J., Mutreja I., Petkov N.
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Juntavee A., Juntavee N., Plongniras P.
Optimization of calcium concentration of saliva with phosphoryl oligosaccharides of calcium (POs-Ca) for enamel remineralization in vitro
Kamasaka H., Kobayashi T., Kuriki T., Matsuo T., Matsuo T., Ohta N., Takii H., Tanaka T., Yagi N.
Gillam D.G., Hill R.
Dentine Hypersensitivity Advances in Diagnosis Management and Treatment Second Edition
Sari Y.W., Yusuf Y., Aminatun, Sari M., Alamsyah K.A., Purnamasari W., Suciati T.
International Journal of Polymeric Materials and Polymeric Biomaterials
Chotimah, Yusuf Y., Sari M., Ana I.D.
Bioengineering
Wei J., Li Z., Wang P., Shi H., Yao H., Luo J., Xu J.
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Ibrahim A.I., Garma N.M.H.
Clinical Oral Investigations
Yusuf Y., Sari M., Nisa A.
Materials Research Express
Chen J., Pan P., Chen L., Chang L., Hu L., Liu Q., Cheng M., Wang C., Liu M., Guo S., Zhang Z., Qi Z., Ding W.
Science of the Total Environment
Satari M.H., Pramanik F., Azhari A.
Open Dentistry Journal
Yusuf Y., Partini J., Wihadmadyatami H., Supii A.I., Jamilludin M.A., Kadek Hariscandra Dinatha I.
Journal of Biomedical Materials Research Part B Applied Biomaterials
Jehad R.H., Abd M.H.
Bionatura
