Mercury and its effect on human health: A review of the literature
Wahyuwibowo J., Zulaikhah S.T., Pratama A.A.
Abstract
Mercury in human body is a free radical that can cause depletion of glutathione (GSH) and hoarding of H2O2, leading to shorten the age of erythrocytes and cause haemolysis. Approximately 90% organic form can be absorbed by the intestinal wall, while inorganic forms are only about 10%. The initial form can also penetrate the blood and placental barrier so that it can cause teratogenic effects and nervous disorders. The effects of mercury toxicity on humans depend on the chemical form of mercury, dosage, age of people exposed, length of exposure, entry into the body, fish diet and consumption of seafood. Mercury is able to bind sulfidril proteins in cells resulting in nonspecific cell injury or even cell death, cessation of microtubule formation, enzyme inhibition, oxidative stress, cessation of protein and DNA synthesis, and autoimmune responses. Classified into a very toxic metal, mercury can trigger the formation of ROS, hydrogen peroxide, lipid peroxidation, hydroxyl radicals that can inhibit enzymes, cell damage, DNA damage, protein structure damage, disruption on the body's antioxidant metabolism, especially superoxide dismutase (SOD) and glutathione peroxidase (GPx). Mercury exposure is associated with an increased risk of hypertension, myocardial infarction, coronary dysfunction, and atherosclerosis. This review is clearly in line to investigate the effect of mercury on human health based on previous research, article and other literature sources.
Mercury, Physical and Chemical Properties
Human health risk assessment of exposure to indoor mercury vapour in a Ghanaian artisanal small-scale gold mining community
Ansah E., Bak J.L., Darko G., Gyamfi O., Sorenson P.B.
Immunotoxicity of mercury: Pathological and toxicological effects
Abdollahi M., Abdollahi M., Abdollahi M., Hassan F.I., Khan F., Maqbool F., Niaz K.
Current progress on understanding the impact of mercury on human health
Basu N., Bose-O'Reilly S., Bose-O'Reilly S., Chan H.M., Dorea J.G., Ha E., McSorley E., Sakamoto M.
Mercury pollution in modern times and its socio-medical consequences
Budnik L.T., Casteleyn L.
The relationship between mercury exposure and epigenetic alterations regarding human health, risk assessment and diagnostic strategies
Abdollahi M., Abdollahi M., Khan F., Khan F., Momtaz S., Momtaz S.
Association between serum heavy metals level and cancer incidence in darbandikhan and Kalar Area, Kurdistan Region, Iraq
Marouf B.
Gender differences in mercury-induced hepatotoxicity: Potential mechanisms
Hazelhoff M.H., Torres A.M.
Genetic aspects of susceptibility to mercury toxicity: An overview
Andreoli V., Sprovieri F.
Prenatal exposure to mercury and longitudinally assessed fetal growth: Relation and effect modifiers
Ballester F., Ballester F., Basterretxea M., Basterretxea M., Fernandez-Somoano A., Fernandez-Somoano A., Guxens M., Guxens M., Guxens M., Guxens M., Iniguez C., Iniguez C., Lertxundi A., Lertxundi A., Llop S., Llop S., Murcia M., Murcia M., Rebagliato M., Rebagliato M., Rebagliato M., Sunyer J., Sunyer J., Sunyer J., Tardon A., Vioque J., Vioque J.
Fu Q., Tu X., Li X., Chang S., Zhu Y., Wang E., Bai Y., Liu J.
Research of Environmental Sciences
Ahmad K., Noorka I.R., Behnassi M., Hameed M.S., Qureshi M.T., Khan B.A., Abdullah F.N.U., Nawaz M.A.
Crop Biofortification Biotechnological Approaches for Achieving Nutritional Security Under Changing Climate
Acharya S.
Food Safety and Quality in the Global South
Adeniran-Obey S.O., Kayode-Edwards I.I., Onwaeze O.O.
Arctic Marine Ecotoxicology Climate Change Pollutants and their Far Reaching Effects
Enuneku A.A., Adeniran-Obey S.O.
Arctic Marine Ecotoxicology Climate Change Pollutants and their Far Reaching Effects
Das C., Debnath S.
Separation and Purification Technology
Negrei C., Mititelu M., Scafa-Udriste A., Busnatu S.S., Andronic O., Neacsu S.M., Ionita-Mindrican C.-B., Lacraru A.-E., Lupuliasa D., Olteanu G.
Toxics
Srinivasan D., Murugesan A., Jaisankar K., Ravi B.
Next Materials
Chai F., Guo L., Yang H., Zhang F., Zhou L., Li Z.
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
Brodziak-Dopierala B., Roczniak W., Babuska-Roczniak M., Fischer A., Wilk Z.
Nutrients
