Effect of tender coconut water on blood lipid levels in high fat diet fed male rats
Brillian Jelita E.M., Alfiza N.S., Pertiwi D., Nuri S., Bagus S.A., Siti Thomas Z.
Abstract
Background: Dyslipidemia is a lipid metabolic disorder characterized by an increased levels of Triglycerides (TG), Total Cholesterol (TC), Low-Density Lipoprotein (LDL)cholesterol, and decreased Hight-Density Lipoprotein (HDL) cholesterol levels. Aim and Objectives: To investigate the effect of the administration of tender coconut water on blood lipid levels in male wistar rats. Material and Methods: Twenty four male wistar rats were randomly divided into four group of six animals each. Group K1 served as control, Group K2 was fed quail egg yolk (1g/rat/day). Group K3 was given coconut water (8 ml/rat/day) orally. Group K4 was given simvastatin (0.18 mg/rat/day) orally for 21 days. Results: that increased levels of TC, LDL and TG with decreased level of HDL were shown in group K2 compared with group K1. Decreased levels of TC, LDL and TG levels were observed significantly in both groups K3 and K4 than K2. Administration of 8ml coconut (200g/kg b w for 21 days) could lower TC, LDL and TG levels with an increased HDL level (p <0.05).Conclusion: The administration of tender coconut water has shown lower total cholesterol, LDL cholesterol and triglyserides levels and increase HDL serum levels in male wistar rats fed a high fat diet.
Therapeutic and Nutritional Values of Narikelodaka (Tender Coconut Water)-A Review
Doddamani S.H., Shubhashree M.N., Venkateshwarlu G.
Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity
d'Uscio L.V., Katusic Z.S., Milstien S., Richardson D., Smith L.
Vitamin C supplementation lowers serum low-density lipoprotein cholesterol and triglycerides: a meta-analysis of 13 randomized controlled trials
McRae M.P.
Vitamin C in the control of hypercholesterolemia in man.
Bobek P., Ginter E., Kubec F., Urbanova D., Vozar J.
L-Arginine inhibits xanthine oxidase-dependent endothelial dysfunction in hypercholesterolemia
Darley-Usmar V.M., Darley-Usmar V.M., Freeman B.A., Freeman B.A., Parks D.A., Parks D.A., Patel R.P., Patel R.P., Shelton J., Tarpey M.M., Tarpey M.M., White C.R., White C.R.
Coconut Water-properties, uses, nutritional benefits in health and wealth and in health and disease: A Review
Lakshmi T.M., Reddy E.P.
The role of coconut water on nicotine-induced reproductive dysfunction in experimental male rat model
Sandhyarajamohan T.
Effect of coconut oil, coconut water and palm kernel oil on some biochemical parameters in albino rats
Luka C.D., Mohammed A.
Antioxidant property and cardiovascular effects of coconut (Cocos nucifera) water
Agbafor K.N., Ale A.B., Elom S.O., Ogbanshi M.E., Oko A.O., Uraku A.J.
Effects of tender coconut water on antioxidant enzymatic superoxida dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and lipid peroxidationi mercury exposure workers
Aniessuwondosantosa A., Zulaikhah S.T., Anies Suwondo A., Santosa, Zulaikhah S.T., Anies, Suwondo A., Zulaikhah S.T., Suwondo A., Zulaikhah ST, Ari SA., Zulaikhah ST, Anies Ari S., Zulaikhah ST.
